(Job 61-21BA)

Ambrx is a clinical-stage biopharmaceutical company with a mission to deliver breakthrough protein therapeutics through our proprietary technology. Unlike conventional conjugation technologies that creates a mixture of suboptimal molecules, Ambrx technology incorporates non-natural amino acids beyond the common twenty into the protein biosynthesis, enabling site specific conjugation of payloads, pharmacokinetic extenders with proteins to create novel homogenous molecular species that is optimized for safety, efficacy and biophysical properties.

The Vice President Accounting Operations & Financial Reporting reports directly to the Chief Financial Officer and is responsible for managing the corporate accounting & financial reporting function on a day-to-day basis.  This includes accounting, external financial reporting, and Sarbanes-Oxley compliance, as well as working closely with the senior management team and external auditors.  Together with the Chief Financial Officer, the Vice President Accounting Operations & Financial Reporting will present accounting matters to the Board of Directors and Audit Committee on an as-needed basis.

 

Primary Responsibilities:

  • Oversees all aspects of day-to-day accounting to ensure accurate and timely financial statement preparation, including maintenance of all accounting systems and functions; reviews the monthly/quarterly financial statements and reviews/approves key account reconciliations.
  • Manages and mentors accounting/finance (including payroll) team.
  • Oversees all accounting strategies, initiatives, and activities, including implementation of new accounting standards and accounting systems.
  • Oversees external reporting requirements including GAAP financial statements, SEC filings (such as Form 20-F, 6-Ks, Proxy, 10-K/10-Q, and others). Manages financials statement audits and quarterly reviews, main liaison with external auditors.
  • Builds financial infrastructure including controls, policies, and processes and leads accounting process improvements, change initiatives, streamlining processes, developing metrics, and creating efficiencies within the department.
  • Ensures maintenance of appropriate internal control environment and accounting procedures, including evaluation of SOX 404 processes and controls.
  • Ensures legal and regulatory compliance regarding all financial & tax functions. Supports and manages company’s tax compliance and tax provision work, in coordination with external advisors.
  • Oversees equity administration and related system, stock-based compensation.
  • Evaluation and implementation of new accounting/financials systems and works closely with internal and external stakeholders.
  • Evaluates and manages company’s contracting process in coordination with Legal department.
  • Manages corporate insurance program and supports company’s risk management program efforts and implementation.
  • Assists in the preparation of materials for management and audit/board committee meetings.

 

 

Job Qualifications:

  • 12+ years of progressive, relevant experience, with a mix of public accounting and public company experience, big 4 experience.
  • Bachelor’s degree / advanced degree in accounting or finance preferred / active CPA.
  • Excellent knowledge of GAAP and SOX is required.
  • ERP and equity administration/stock-based compensation system experience; preferably Great Plain, Microsoft Dynamics 365, NetSuite and other comparable systems.
  • Previous experience in Biotech industry preferred.
  • Excellent interpersonal, written, and verbal communication skills.
  • Ability to pivot and work well in fast-paced environment, with significant growth.
  • Strong leadership and influence skills with a demonstrated business partnering approach.
  • Experienced people manager with proven ability to attract, retain and develop talent.

 

To be considered for this opportunity, please submit your resume/CV referencing the position code to careers@ambrx.com. Applicants whose qualifications and experiences most closely match the requirements will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensations & benefits. EOE.

Job Code: 60-21BA

About Ambrx:

Ambrx Inc., is a clinical-stage biopharmaceutical company focused on developing Precision Biologics using an expanded genetic code. Ambrx technology uses an expanded genetic code to incorporate synthetic amino acids into proteins, all completed within a living cell. These synthetic amino acids enable the creation of Precision Biologics, an exciting new class of therapeutics with broad application and potential. This includes next-generation antibody drug conjugates (ADCs), bispecifics, targeted immuno-oncology therapies, immunomodulatory smart cytokines, and long-acting therapeutic peptides for metabolic and cardiovascular disease.

Overall Responsibilities:

We are seeking a highly motivated leader to be a key member of a fast-paced and dynamic organization. This position is a Clinical Development Leader who is a clinical development physician who plays a key role on the cross-functional drug development team.  This role will lead and advance the clinical development programs, in various Oncology indications through early development to global regulatory submissions.

The level will depend on the experience.

Specific Responsibilities:

  • Lead Clinical Development Strategy and Planning and demonstrate ownership of study designs and hands-on implementation in support of the overall product development plan, based on strong cross functional collaboration, clinical and scientific principles, knowledge of compliance and regulatory requirements, markets and emerging issues
  • Responsible for hands-on implement clinical trials, protocol related documents development, clinical data review, and other study execution activities
  • Prepare and present research data, lead and participate in the discussion of the strategies in tumor types such as breast, gastric, prostate, bladder, RCC, NSCLC, ovary, biliary and pancreatic cancers.
  • Lead clinical study teams, monitor overall study integrity, and review, interpretation, and communication of efficacy and safety data
  • Present at scientific, clinical, and regulatory meetings globally
  • Develop and maintain relationships with academic investigators, pharmaceutical and/or biotech partners/sponsors, KOL’s, and patient advocacy groups
  • Contribute to regulatory filings including authoring clinical sections for INDs, BLAs, NDAs, and other related documents
  • Collaborate closely with relevant functions including statistics and data science, clinical operation, regulatory and quality assurance, clinical pharmacology, drug safety & pharmacovigilance, Pre-clinical, CMC and other cross-functional teams.
  • Maintain a high level of clinical and scientific expertise in the disease area(s) by reviewing the literature, attending medical/scientific meetings, and through personal interchanges with consultants, thought leaders, investigators and internal stakeholders
  • Author manuscripts and collaborate with cross-functional colleagues and thought leaders to meet publication plan objectives
  • Establish strong working relationships and collaborations with study investigators, key opinion leaders in drug development, external partners, and CROs.

Qualifications:

  •  MD required
  • Must have at least 8-15 years of experience as a high-performing hands-on physician with clinical development experience in conducting oncology clinical studies
  • Experience with ADCs (Antibody drug conjugates) is a plus
  • Must have a strong track record leading clinical trials efficiently and collaboratively with cross-functional teams, with excellent verbal and written communication skills
  • Must have outstanding presentation skills
  • Must maintain the highest level of data quality and integrity, to meet all relevant regulatory and health authority inspection requirements

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. EOE

Job Code: 59-21BA

Ambrx is a clinical-stage biopharmaceutical company with a mission to deliver breakthrough protein therapeutics through our proprietary technology. Unlike conventional conjugation technologies that creates a mixture of suboptimal molecules, Ambrx technology incorporates non-natural amino acids beyond the common twenty into the protein biosynthesis, enabling site specific conjugation of payloads, pharmacokinetic extenders with proteins to create novel homogenous molecular species that is optimized for safety, efficacy and biophysical properties.

Ambrx is seeking a highly motivated and dedicated Accounting Supervisor / Associate Accounting Manager to be a key member of the Finance team in a fast-paced and dynamic environment. The Accounting Supervisor / Associate Accounting Manager will ensure accurate and timely processing and recording of the company’s financial transactions and ensures compliance with internal controls.

 

Primary Responsibilities:

  • Responsible for month-end closing process and preparation of consolidated financial statements.
  • Analysis of monthly general ledger account activity, journal entries, accruals, and reconciliation of GL accounts.
  • Calculate, analyze, and prepare journal entries for R&D contract accruals, based on CMO and CRO agreements. Liaise with internal and external project managers for monthly analysis and to resolve issues.
  • Manages consolidations and intercompany transactions.
  • Prepare bank reconciliations for multiple entities, using Great Plains.
  • Responsible for Fixed Asset process, including additions and disposals, and running quarterly depreciation, using Great Plains.
  • Maintain various spreadsheets, using advanced Excel formulas and pivot tables, to support financial transactions and analysis of various expenses.
  • Participate in annual budget process and budget vs. actual reporting.
  • Supervises AP staff and manages AP process and procedures.
  • Supports and prepares work papers for annual financial audit and related tax provision and tax return. Correspond with external auditors and tax firm as required.
  • Tax compliance support for Use Tax, Property Tax, and other city/state reporting, as needed.
  • Develops and implements workflow process improvements and internal controls, including documentation of desktop procedures.
  • Assist with special, ad-hoc projects as needed.
  • Respond to internal and external customer requests as appropriate.
  • Other duties as assigned.

 

Job Qualifications:

  • BS degree in accounting or finance
  • Minimum of 5+ years of progressive experience in Accounting
  • Active CPA
  • Previous experience in Biotech industry & public company experience, Big 4 experience preferred
  • Solid understanding of U.S. GAAP and Sarbanes-Oxley
  • Ability to research and interpret accounting guidance
  • Strong knowledge and experience using Microsoft Dynamics GP (Great Plains)
  • Excellent analytical skills, attention to detail, and organization
  • Advanced Excel skills (e.g. pivot tables, VLOOKUP, array formulas etc.)
  • Self-starter with the ability to work independently with little supervision and knows when to ask for advise
  • Excellent written, verbal and interpersonal communication skills

 

 

To be considered for this opportunity, please submit your resume/CV referencing the position code to careers@ambrx.com. Applicants whose qualifications and experiences most closely match the requirements will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensations & benefits. EOE.

(Job Code: 58-21BA)

Ambrx is a clinical-stage biopharmaceutical company with a mission to deliver breakthrough protein therapeutics through our proprietary technology. Unlike conventional conjugation technologies that creates a mixture of suboptimal molecules, Ambrx technology incorporates non-natural amino acids beyond the common twenty into the protein biosynthesis, enabling site specific conjugation of payloads, pharmacokinetic extenders with proteins to create novel homogenous molecular species that is optimized for safety, efficacy and biophysical properties.

Ambrx is seeking a highly motivated and dedicated Payroll Supervisor / Sr. Accountant to be a key member of the Finance team in a fast-paced and dynamic environment. The Payroll Supervisor / Sr. Accountant will ensure accurate processing and recording of the company’s payroll, provide timely and accurate financial information, daily data entry and perform related work as required.

Major Responsibilities:

  • Manages biweekly payroll process with 3rd party payroll processor that includes importing, proofing, editing, processing and transmitting of payroll and related payroll deductions, reimbursements, bonuses, and manual payments consistent with federal and state wage and hour laws
  • Provides excellent customer service to employees: in the areas of compensation, taxes, benefits, time-tracking, how to request time off, etc.
  • Performs updates to payroll-related information and data and manages overall payroll work flow
  • Ensures timely processing of all new hires, promotions and terminations and other changes to payroll data
  • Analyzes and audits payroll data for accuracy of posting, including intercompany transactions.
  • Prepares journal entries related to payroll and benefits and records it timely and accurately
  • Processes 940/941 tax payments
  • Processes accurate and timely year end reporting (W-2, W-2c, etc.)
  • Develops ad hoc financial and operational reporting as needed
  • May assist with audits of internal records, workers compensation, tax filings and related documentation.
  • Documents payroll processes and procedures; may train payroll/finance department staff and supports new hire onboarding process
  • Supports equity administration matters as assigned
  • Manages T&E process and reimbursements.
  • Supports month-end closing process and preparation of consolidated financial statements.
  • Preparation, support, and analysis of monthly general ledger account activity, journal entries, accruals, and reconciliation of GL accounts as assigned.
  • Supports annual financial audit and quarterly reviews of the company.
  • Assist in development and implementation of workflow process improvements.
  • Assist with special, ad-hoc projects as needed.
  • Other assigned duties

Job Qualifications:

  • BS in business, accounting or relevant field, or equivalent years of experience
  • Previous experience in Biotech industry & public company experience preferred
  • Minimum of 3-5 years of experience in Payroll
  • Minimum of 3+ years of progressive experience in Accounting
  • Proven experience as payroll specialist or payroll manager/supervisor
  • Very good knowledge of legislation and regulations of the payroll field
  • Solid understanding of accounting fundamentals and payroll best practices
  • Strong knowledge of ADP payroll software (Workforce Now), knowledge of other payroll systems such as Paylocity is a plus
  • Experience with T&E reporting software (i.e. Concur) a plus
  • Trustworthy with attention to confidentiality
  • Outstanding organizational ability with great attention to detail
  • Excellent communication skills (oral and written) and team player
  • Advanced computer skills in MS Office
  • Experience using Microsoft Dynamics GP (Great Plains)
  • Ability to work independently with little supervision

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experiences most closely match the requirements will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. EOE.

Job: 57-21BA

About Ambrx:
Ambrx, Inc. is a biopharmaceutical company with a mission to deliver breakthrough protein
therapeutics. Ambrx is based on a fundamental advance in protein biosynthesis that enables the
company to genetically engineer proteins with new amino acid building blocks beyond the common
twenty, enabling the biosynthesis of proteins with new physical, chemical and pharmacological
properties. At Ambrx, we are dedicated to assembling and developing an exceptional team and a
breakthrough technology to create the next generation of protein-based medicines.

KEY RESPONSIBILITIES
• Independently design and perform in vitro binding and cellular assays to assess drug
candidate cytotoxic and/or immunomodulatory effects
• Analyze and interpret experimental results and present findings at project team meetings
• Provide technical expertise to project teams for functional assay development,
immunoassay design, flow cytometry, and/or other specialized techniques
• May support management of external studies with CROs and/or collaborators
• Maintain detailed records in laboratory notebooks in accordance with company policy
• Contribute to writing of technical reports, SOPs, patent applications, and scientific
manuscripts for publication

PROFESSIONAL EXPERIENCE/QUALIFICATIONS
• B.S. in Biology/Biochem or similar + 6 years industry experience; or M.S. + 4 years industry
experience
• Consistent track record of rigorous in vitro agonist/antagonist study design, including
appropriate controls, benchmarks, dose responses, variability, reproducibility, etc.
• Deep experience performing in vitro functional assays using cell lines and primary human
immune cells (e.g. cytotoxicity, immune-tumor cell co-culture, immune activation)
• Independent proficiency in diverse laboratory techniques, including cell culture, flow
cytometry, ELISA/MSD/HTRF/etc, and primary human immune cell isolation
• Demonstrated ability to analyze complex data sets and concisely and communicate results
• Excellent organizational, time-management, and multi-tasking skills
• Consistently uses analytical thinking, persistence, and creativity to overcome challenges
• Demonstrated ability to deliver decision-making data sets within a matrixed organization
• Excellent verbal and written communication and interpersonal skills

How to Apply
To be considered as an applicant, please submit your resume/CV referencing the specific position of
interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most
closely match the position requirements will be contacted for further evaluation. Ambrx offers
competitive compensation & benefits. EOE

Job 56-21BA

About Ambrx:

Ambrx, Inc. is a biopharmaceutical company with a mission to deliver breakthrough protein therapeutics. Ambrx is based on a fundamental advance in protein biosynthesis that enables the company to genetically engineer proteins with new amino acid building blocks beyond the common twenty, enabling the biosynthesis of proteins with new physical, chemical and pharmacological properties. At Ambrx, we are dedicated to assembling and developing an exceptional team and a breakthrough technology to create the next generation of protein-based medicines.

KEY RESPONSIBILITIES

  • Independently contribute to drug discovery project planning, advancement, and leadership
  • Design and perform in vitrobinding and cellular assays to assess drug candidate effects on innate and adaptive immune functions
  • Analyze and interpret experimental results and present findings at project team meetings
  • Provide subject matter expertise to diverse project teams related to basic immunology, immuno-oncology, target biology, and disease pathogenesis
  • Use competitive intelligence, analytical thinking, and domain expertise to develop new project proposals
  • Support and manage external collaborations, including CROs and collaborators
  • Desirable: may contribute to design and execution of in vivopharmacology models
  • Manage daily activities and professional development of one or more Research Associates
  • Maintain detailed records in laboratory notebooks in accordance with company policy
  • Write and review technical reports, SOPs, and scientific manuscripts for publication

PROFESSIONAL EXPERIENCE/QUALIFICATIONS

  • PhD degree in Immunology (or Mol/Cell Biology/Biochem with immunology expertise)
  • For Sr. Scientist: 5+ years of industry drug discovery experience
  • Deep understanding of human immunology and immuno-oncology field
  • Experience designing and performing in vitro assays using cell lines and primary human immune cells, including multi-step stimulation and immune-tumor cell co-culture systems
  • Skilled in standard immunological, and cell biology techniques including flow cytometry, ELISA/MSD/HTRF/etc, and primary immune cell isolation and culture
  • Experience with in vivo pharmacology systems is preferred
  • Demonstrated ability to organize and communicate complex data sets concisely
  • Excellent organizational, time-management, and multi-tasking skills
  • Consistently uses analytical thinking, persistence, and creativity to overcome challenges
  • Demonstrated ability to progress projects within a complex, matrixed, organization
  • Excellent verbal and written communication and interpersonal skills

 

How to Apply

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most closely match the position requirements will be contacted for further evaluation. Ambrx offers competitive compensation & benefits.  EOE

 

(Job 54-21BA)

Ambrx is a clinical-stage biopharmaceutical company with a mission to deliver breakthrough protein therapeutics through our proprietary technology. Unlike conventional conjugation technologies that creates a mixture of suboptimal molecules, Ambrx technology incorporates non-natural amino acids beyond the common twenty into the protein biosynthesis, enabling site specific conjugation of payloads, pharmacokinetic extenders with proteins to create novel homogenous molecular species that is optimized for safety, efficacy and biophysical properties.

Ambrx is seeking a highly motivated and dedicated Associate Scientist to be a key member of the In Vivo – Pharmacology team in a fast-paced and dynamic environment. This position will be responsible for conducting in vivo pharmacology experiments.

Major Responsibilities:

  • Independently conduct rodent in vivo pharmacology experiments, including but not limited to initiating, maintaining, and evaluating oncology models, including model development, dosing for PK/PD relationships and efficacy studies – with blood sampling, and tissue/tumor collection endpoint analysis for FACS analysis, IHC etc.
  • Author study reports in a timely manner and assist in maintaining and organize report repository.
  • Effectively present experimental data with concise results to guide drug development at organizational meetings.
  • Work as part of a collaborative team to design, plan and execute experiments that support research activities.
  • Assist in IACUC documentation preparation and renewal and vivarium compliance.
  • Interface with external laboratories for testing and sample analysis when required.

 

Job Qualifications:

  • BS/MS with 3+ years related experience.
  • Highly skilled in various methods of dosing (SC, IP, IT, PO, and IV) and blood collection (RO, tail vein, and cardiac puncture) in mice primarily, but occasional rat studies.
  • Strong experience in tumor measurements by caliper, body weighing, and health monitoring. Must be experienced with precise dosage calculations for in vivo efficacy studies.
  • Familiarity in harvesting and disaggregating tissue / tumor for subsequent ex vivo analysis – experience with multi-color FACS analysis a plus.
  • Familiar with software including Graph Pad, Microsoft office etc. for data analysis and data summary and presentation.
  • Adaptive and a quick learner, efficient in multitasking, highly organized and excellent record keeping.

 

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experiences most closely match the requirements will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. EOE.

 (Job 36-21BA) 

Ambrx Inc., is a clinical-stage biopharmaceutical company focused on developing Precision Biologics using an expanded genetic code. Ambrx technology uses an expanded genetic code to incorporate synthetic amino acids into protein, all completed within a living cell. These synthetic amino acids enable the creation of Precision Biologics, an exciting new class of therapeutics with broad application and potential. This includes next-generation antibody drug conjugates (ADCs), bispecifics, and targeted immuno-oncology therapies for cancer as well as smart cytokines to modulate the immune system, and long-acting therapeutic peptides for metabolic and cardiovascular disease. 

Ambrx is seeking 2 highly motivated Senior Research Associates to join the Discovery Group. The primary responsibility is to support multiple oncology and immune-oncology projects from discovery to the preclinical phase. The candidate will work in a multidisciplinary and dynamic team environment to help with discovery and develop precision engineered biological drugs that change patients’ lives. 

Major Responsibilities: 

  • Work in the Discovery Group to support multiple discovery projects to expand Ambrx’s early pipeline 
  • Build DNA constructs for various formats of biological therapeutics 
  • Collaborate seamlessly with cell culture group to quickly deliver protein material for discovery projects 
  • Generate recombinant stable cell lines for assay development and preclinical animal models 
  • Develop and perform in vitro biological assays to characterize drug candidates 

Job Requirements: 

  • MS degree with 4+ years of experience, or BS degree with 6-8 years of experience, in the biotech and /or pharmaceutical industry 
  • Expertise in molecular biology, especially in cloning, PCR, and vector construction 
  • Expertise in recombinant protein expression in a wide variety of systems (bacterial, mammalian cells) 
  • Excellent skills in aseptic tissue culture, in vitro biological assays, ELISA 
  • Hands-on experience in FACS based assays 
  • Prior experience in stable cell line generation and assay development is desired 
  • Prior experience working with oncology and immune-oncology therapeutic proteins and translational science is a plus 
  • Demonstrated passion to learn and advance new technology 
  • Ability to work independently and collaboratively in a matrixed team environment 
  • Good oral/ written communication and strong problem-solving skills 

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits. 

(48-21BA)

Ambrx is a clinical-stage biopharmaceutical company enabling new field of protein medicinal chemistry using an expanded genetic code to produce high value biological products such as long-acting proteins, antibody drug conjugates and bi-specific antibodies.

Ambrx is seeking a highly motivated research scientist to join the Targeted Biologics Development Team. The main job responsibility is to express engineered proteins to support multiple oncology and immune-oncology projects from discovery to preclinical phase. The candidate will work in a multidisciplinary and dynamic team environment to help with the discovery and development of precision engineered biological drugs that change patients’ lives.

Primary Responsibilities:

  • Support multiple discovery projects both intellectually and experimentally to expand Ambrx’s early pipeline
  • Build DNA constructs for various formats of biological therapeutics
  • Collaborate seamlessly with cell culture group to quickly deliver protein material for discovery projects
  • Generate recombinant stable cell lines for assay development and preclinical animal models
  • Develop and perform in vitro biological assays to characterize drug candidates

Requirements:

  • PhD degree in biology/biochemistry or related discipline with 1-3 years of drug discovery experience in the biotech and /or pharmaceutical industry
  • Expertise in molecular biology, especially in cloning, PCR, and vector construction
  • Expertise in recombinant protein expression in a wide variety of systems (bacterial, mammalian cells)
  • Excellent skills in aseptic tissue culture, in vitro biological assays, ELISA
  • Hands-on experience in FACS based assays
  • Prior experience in stable cell line generation and assay development is desired
  • Prior experience working with oncology and immune-oncology therapeutic proteins and translational science is a plus
  • Demonstrated passion to learn and advance new technology
  • Ability to work independently and collaboratively in a matrixed team environment
  • Good oral/ written communication and strong problem-solving skills

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits.

(46-21BA)

Ambrx is a clinical-stage biopharmaceutical company enabling new field of protein medicinal chemistry using an expanded genetic code to produce high value biological products such as long-acting proteins, antibody drug conjugates and bi-specific antibodies.

We are seeking a highly creative and motivated organic/medicinal chemist to be a key member of dynamic research organization. The successful candidate will be part of a growing chemistry team who can contribute to discovering novel protein therapeutics to help patients in need.

Primary Responsibilities:

  • The successful candidate will support our small molecule, linker, and peptide synthesis needs
  • Carryout structure-activity relationship studies delivering high quality material for biological testing
  • Interpret experimental results such as in vitro/in vivo data to support new compound design and SAR
  • Carryout analytical and preparative method development to support internal chemistry needs
  • Collaborate and interface with other functional areas including analytical, biology and pharmacology to facilitate development and execution of project plans
  • Communicate research findings to the key stake holders and present in project meetings/conferences
  • Contribute to patent application writing and research reports
  • Identify and establish working relationships with CROs and manage external chemistry resources
  • Safe keeping and operation of lab and lab equipment

Qualifications:

  • Ph.D. in organic/medicinal chemistry or related field with minimum 2-6 years of post-doctoral/industry experience
  • Proven track record in drug discovery and demonstrated success in Hit/Lead identification and optimization, and carrying out SAR studies
  • Experience in structure-based and pharmacophore-based drug designs
  • Experience in modern synthetic organic chemistry techniques, designing new synthetic routes for complex molecules and carrying out multi-step synthesis of biologically active molecules
  • Hands-on experience with analytical and purification equipment HPLC, LC-MS and NMR etc.
  • Experience working with antibody drug conjugates is a plus
  • Must have strong presentation skills
  • Excellent communication, organization and collaborative skills are essential

To be considered as an applicant, please submit your resume/CV referencing the specific position of interest and position code to careers@ambrx.com. Applicants whose qualifications and experience most closely match the requirements of the position will be reviewed. Candidates will only be contacted for evaluative discussions. Ambrx offers competitive compensation & benefits.