About Us

At Ambrx, our mission is to discover and develop a pipeline of Engineered Precision Biologics to treat a broad range of diseases and disorders, with an initial focus on cancers with a high unmet medical need.

Our internal pipeline is focused on creating antibody-drug conjugate and immune-oncology conjugate candidates, including ARX788: our most advanced internal ADC candidate currently being studied broadly in breast cancer, gastric/GEJ cancer and other solid tumor trials. We have established collaborations with multiple pharmaceutical companies in additional therapeutic areas, including metabolic disorders and cardiovascular disease.

Our team of dedicated professionals is bound by a culture and vision that embraces innovation, practicality and accountability. Through these shared values, we are able to relentlessly pursue our mission of bringing engineered precision biologics to patients facing the need for new treatment options. Visit our Careers page for information about joining our team.

What is an Engineered Precision Biologic?

EPBs are therapies we create using our expanded genetic code technology platform. Harnessing the power of this proprietary technology, we are able to precisely incorporate novel synthetic amino acids (SAA) in proteins, all within a living cell. The result is product candidates specifically designed to overcome the inherent limitations of conventional conjugation approaches that use natural amino acids for non-site-specific conjugation – offering potential safety and efficacy benefits to patients.